Nuno is one of my all time favorite guitarists.
The playfulness and energy combined with a great sense of melody makes him one of the best in my book.
I'm using a Kemper profile of a Marshall JCM800 made by Till Schleicher and I think it's free in the Rig Exchange. There's an added Rat before the amp and a Noise Gate. I tweaked it a bit to get as close to the original guitar tone as possible, but I couldn't get it perfect. It was actually difficult to play with this amount of gain and top end.
You can find the backing track without any guitars here
https://www.youtube.com/watch?v=Th_MVZTyo2E&ab_channel=Backingtracks
I haven't really played guitar lately, so I got blisters on my fingertips. Therefore the band aid :P